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diagnosis causes hemolysis hepatology injury liver thrombocytosis classification elevation erythematosus extravascular gap globulin hepatitis intravascular lactate lactic lupus platelets protein
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... immune-complex hemolytic anemia ... • Acute HTR ... Prosthetic heart valves ... #Causes #Hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Other: NAFLD, Autoimmune ... Liver #Injury #Differential ... #algorithm #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Membrane): - Autoimmune ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... , deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Autoimmune: ... Autoimmune hepatitis ... #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... to bolus these values ... presentations and disease ... peritonitis - Acute ... 30mmHg) - Severe anemia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... • Non-autoimmune ... deficiencies • Autoimmune ... lymphopenia, low PLT • Anemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Viral infections (acute ... Cirrhosis, ETOH, autoimmune ... Thalassemia, Sickle cell anemia ... inflammation (acute ... Gap #ProteinGap #differential
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