42 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... Cold AIHA • PCH ... anemia • ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... • Bleeding • Hemolysis ... Renal Disease, Liver ... Reticulocytosis • Liver ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Liver disease, ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Liver diseases ... spherocytosis, Hemolytic ... , Liver diseases ... key #diagnosis #differential ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... cold agglutin disease ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... , CKD • Hemolytic ... Non-megaloblastic: Liver ... disease, Alcoholism ... #Diagnosis #hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Hypothyroid • Liver ... Disease • Alcohol ... #Macrocytic #Anemia ... #differential # ... diagnosis #algorithm #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Differential Diagnosis ... Cold Agglutinin Disease ... #Table #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell disease ... #Anemia #Differential ... Algorithm #workup #hematology