13 results
diagnosis coagulation algorithm aptt hemolysis hepatology intravascular prolonged pt arterial arteritis biliary bleeding bruising cholangitis cirrhosis dic disseminated embolism extravascular
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... Cold AIHA • PCH ... Prosthetic heart valves ... #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... function may be abnormal
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... deficiency • Liver ... #Diagnosis #hematology ... #nonpalpable #dermatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Syndrome, Ischemic Liver ... atherosclerotic lesions ... coagulation and other causes ... pathophysiology #hematology ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... malignancies, Hepatic
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... • Reduced liver ... amyloidosis #Abnormal ... #hematology #coagulation
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Acquired: • Heparin ... discern these causes ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
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