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diagnosis hematology classification elevation hemolysis injury macrocytic acidosis acute alkaline alp biliary cholangitis cirrhosis diarrhea dili disease elevatedmcv extravascular fattyliver
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... • Alcohol • Drugs ... #differential # ... diagnosis #algorithm ... #hematology #workup
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Deficiency • Drugs ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... immune-complex hemolytic anemia ... Prosthetic heart valves ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... Blood Smear • Drugs ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... , PCH, Evans Syndrome ... , Liver Disease, ... Defects: Sickle cell anemia
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , Recreational Drugs ... #Acute #algorithm ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Intestine - Other causes ... Cholestasis - Drugs ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Causes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... bile ducts Differential ... , Sarcoidosis, Drug-induced ... cholangitis #diagnosis #workup ... #hepatology
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