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diagnosis liver algorithm transaminitis injury interpretation abnormal causes chemistry disease drug elevated elevation fattyliver function functiontest gastroenterology hepatitis idiosyncratic induced
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... #LFTs #Hepatocellular ... #diagnosis #differential ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Calculate R-Value ... • Hepatocellular ... • Cholestatic DILI ... Idiosyncratic #differential
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... abnormality vs bone Bili ... ALP ≥ 2x ULN R Value ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... • Iatrogenic: DILI ... Source of Liver Enzyme ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Transaminitis Hepatocellular ... dz Cholestatic ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... Source of Liver Enzyme ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Others • Cholestatic ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... ) - Normal Values ... , intrahepatic cholestasis ... , hepatocellular ... Interpretation #diagnosis #hepatology
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... 4, fibrosis-4; HCC ... , hepatocellular ... algorithm #Referral #Management ... #Hepatology
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