14 results
diagnosis hematology algorithm treatment anemia causes hemolysis hemolytic hepatitis rheumatology acquired agglutinin aiha cold dili drug erythematosus extravascular fattyliver gastroenterology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
• Alloimmune ... HTR • Drug-induced ... • PCH ... PNH • Drug-induced ... Prosthetic heart valves
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... • Drugs • AIH ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... Drug-associated, PCH
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis of Autoimmune ... >1.5, and both values ... Possible drug-induced ... Hepatitis #Diagnosis #Hepatology ... #AIH
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... esp if severe disease ... , Splenectomy, MMF ... Treatment #management ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune ... disease • vWF ... • Shear stress-induced ... #differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... from subclinical disease ... been reported (eg AIH-PBC ... #Diagnosis #Management ... #Hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
women • 15% of AIHA ... Viral infection, autoimmune ... Presentation - Cold-Induced ... Acrocyanosis (Cold-induced ... pts) Differential
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... markers such as ELF ... 4, fibrosis-4; HCC ... algorithm #Referral #Management ... #Hepatology
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