12 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential ... Diagnosis Algorithm ... • MAHA (TTP ... Prosthetic heart valves ... #Causes #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... TTP/HUS indicates ... thrombocytopenic purpura/hemolytic ... 2012, p 193 #Diagnosis ... #Differential #
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Fragmentation - MAHA: TTP ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity - A low value ... If the value is ... WBC count and differential ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... thrombocytopenia - DIC, TTP ... #Anemia #Differential ... #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... for workup, including ... blood loss, Acute hemolysis ... Rebound effect from treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Antibiotics (Bactrim, PCN ... injury, ischemia, hemolysis ... reabsorption) Workup ... Pseudohyperkalemia - hemolysis ... #potassium #nephrology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... myasthenia Diagnosis ... Serologic and EMG ... Myasthenia #Gravis #diagnosis ... #management #neurology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
WAIHA • CAD • PCH ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
antibody that works ... autoantibodies - TPO, TTG ... Person Syndrome Treatment ... #Management #treatment ... #neurology