12 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
) - Causes of Hepatocellular ... skeletal muscle and kidney ... • R value = (ALT ... Transaminitis #diagnosis #differential ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... : - Enzymes that ... Intestine - Other causes ... Intestine • Kidney ... Diagnosis #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Algorithm Vascular Causes ... Source of Liver Enzyme ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Source of Liver Enzyme ... Cardiac muscle, Kidneys ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... elliptocytosis - RBC Enzyme ... Cold AIHA • PCH ... Prosthetic heart valves ... #Hematology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Bacteremia, Sepsis • Kidneys ... Resp/Heme: CHF, valves ... Polyneuropathy, ALS ... #Diagnosis #causes ... #neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... tubule of the kidney ... respiratory failure • Neurologic ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... Miller Fischer and PCB ... Serologic and EMG ... diagnosis #management #neurology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
No structural kidney ... Exclude other AKI causes ... evaluation essential in all ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis