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Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Resp/Heme: CHF, valves ... , COPD, ILD, OSA ... NMJ disorder (Myasthenia ... Diagnosis #causes ... #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Diagnosis Algorithm ... #Neurology #Differential ... #Causes
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Diagnosis - ... Serologic and EMG ... precipitated by: Drugs, infection ... #Gravis #diagnosis
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... pulmonary etc) • CNS ... of the spinal cord ... Postsynaptic: Myasthenia ... Diagnosis #neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Cord: Demyelinating ... Eaton Syndrome, Myasthenia ... #Causes #differential ... #diagnosis #neurology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Muscle Weakness ... neurologic disease • Myasthenia ... Sarcoidosis • Infections ... #differential # ... causes #neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Chorioretinitis • Diagnosis ... PCR 50% sensitive ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Acute and Chronic Causes of Dyspnea - Differential Diagnosis Pulmonary/Chest Wall: • Acute: Trauma, COPD exacerbation, Asthma
Acute and Chronic Causes ... Diagnosis Pulmonary ... , Anaphylaxis, Infection ... hernia, Obesity CNS ... Neuromuscular disease (eg myasthenia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... circulation - Infections ... AIHA • PCH ... Prosthetic heart valves
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... Diagnosis Algorithm ... Hemorrhage • CNS ... Infection ... and Transient Myasthenia
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