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Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Sensory Changes - Differential ... Neuropathy • Spinal ... • Congenital Myopathy ... #Neurology #Differential
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... neurologic disease • Myasthenia ... mimics #diagnosis #differential ... #causes #neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Eaton Syndrome, Myasthenia ... Mitochondrial myopathy ... #Causes #differential
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Resp/Heme: CHF, valves ... I am weak": • Myopathy ... NMJ disorder (Myasthenia ... Diagnosis #causes ... #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
crises”. ... life-threatening Differential ... Serologic and EMG ... bulbar weakness ... diagnosis #management #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
More likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... Sinai Hospital of ... diagnosis #management #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Lesions of the spinal ... Postsynaptic: Myasthenia ... Myopathy: ... #Differential #
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential ... /paralysis - Weakness ... Cord Causes: 1 ... disorders #diagnosis #neurology ... #differential
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
Causes of spinal ... • Extrinsic Causes ... - Radiation myelopathy ... syndromes #lesions #differential ... #diagnosis #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
• MCC- acute ... - Emergency Causes ... lower extremity weakness ... #diagnosis #causes ... #neurology
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