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liver algorithm transaminitis acute hematology hepatocellular acidosis arterial autoimmune biliary chemistry cholangitis cholestatic cirrhosis classification dili elevation embolism enzymes extravascular
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... obstruction - Drug-Induced ... #Differential # ... Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... ) - Differential ... 1000): • DILI (Drug-induced ... liver injury) ... Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , Recreational Drugs ... Diagnosis #Causes ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Bile Ducts • PSC ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... • R value = (ALT ... Transaminitis #diagnosis ... #differential # ... hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... valproate, azoles), Drugs ... Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... Cold AIHA • PCH ... Prosthetic heart valves ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... #hepatitis #differential ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
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