15 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... Calculate R-Value ... #differential # ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #differential # ... #hepatology
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... #Acute #Liver # ... Differential #Incidence
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Diagnosis Framework ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Hepatic Masses on CT - Differential Diagnosis by CT Findings

Masses: Hemangioma, Adenoma, FNH, HCC, Fibrolamellar HCC,
- Differential ... Diagnosis by CT ... #CTA #differential ... #diagnosis #liver ... #hepatology #radiology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Injury ... • R value = (ALT ... Transaminitis #diagnosis ... #differential # ... hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
abnormality vs bone Bili ... ALP ≥ 2x ULN R Value ... Hepatocellular injury ... Transaminitis #diagnosis ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... #Injury #Differential ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
LFTs) - Normal Values ... bilirubin (Conjugated/DBili ... hepatocellular injury ... Interpretation #diagnosis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Unconjugated Bili ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis