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management transaminitis acidosis algorithm causes chemistry children cholestatic classification dili drug elevation embolism enzymes gastroenterology hematology hepatocellular idiosyncratic induced interpretation
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... Liver Injury ... • R value = (ALT ... #differential # ... hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Calculate R-Value ... #differential # ... gastroenterology #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... Diagnosis Framework ... Syndrome, Ischemic Liver ... Vasculitis • Injury ... #differential #
Liver Abscess and Mimics - Differential Diagnosis Most Common: Polymicrobial, E Coli, Klebsiella, Strep/Enterococcus, Staph, Anaerobes Infectious Differential:
Liver Abscess and ... : - Bacterial: ... Non-Infectious: HCC ... #Abscess #Differential ... #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... children Common bacterial ... ) • Traumatic injury ... children #peds #differential ... #diagnosis #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... or renal injury ... ’s • Reduced Arterial ... Injury: • Reduced
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