27 results
hematology algorithm causes management treatment hemolytic pulmonary activetb chronic extravascular intravascular latenttb pain rheumatology tb tuberculosis abdominal abscess agglutinin ascites
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... e.g. lupus, CLL, lymphoma ... Extravascular #Causes #differential ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential ... Diagnosis Algorithm ... AIHA • PCH ... anemia • ... Prosthetic heart valves
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Monoclonal - Lymphoid ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential ... #hemolytic #anemia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Cell Agglutinate: Cold ... cold hemoglobinuria ... , Malignant lymphoma ... RBC #Morphology #differential ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH ... Defects: Sickle cell anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold ... #Anemia #Differential ... #workup #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 ... deficiency • Fanconi’s anemia ... telomeropathy Cancer ... • Leukemia • Lymphoma ... Antibody-mediated hemolysis
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm • GI disorders: Celiac disease, Crohn's disease,
Nephropathy - Differential ... Diagnosis Algorithm ... : IgA myeloma, Lymphomas ... , RCC, Lung Cancer ... Pulm disorders: COPD
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... blood loss, Acute hemolysis ... , deficiency anemia ... Malignancy: Metastatic cancer ... , Lymphoma, Rebound
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... - Prosthetic valves ... Malignancy: • Lymphomas ... #diagnosis #Laboratory
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