14 results
hematology management algorithm causes hemolysis acidosis acquired apml arteritis cancer cap chronic cll community differentiation dyspnea elevation erythematosus extravascular gap
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Neutropenia, anemia ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis ... #workup #oncology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... • Sickle cell ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... Prosthetic heart valves
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... : - Heart valves ... - Cytopenias (anemia ... dyspnea #algorithm #differential ... #diagnosis #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... fluid overload, PCC ... management #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #classification ... #hematology #oncology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... very remarkable w/differential ... systemic complaints- anemia ... Treatment of GCA
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... to bolus these values ... 30mmHg) - Severe anemia ... #typea #typeb #classification
Community Acquired Pneumonia (CAP) - Diagnosis and Management Pneumonia Signs/Symptoms: • Confusion/disorientation (LR + 1.9) • Cough
Pneumonia (CAP) - Diagnosis ... Bands > 15% • Uremia ... negative predictive value ... cultures/nasal PCR ... #Management #treatment
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