18 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
50%): Pleurisy / effusion ... Demyelinating syndromes ... #erythematosus ... signs #symptoms #diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Lungs: • Pleural effusions ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... lupus erythematosus ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
(e.g. eclampsia ... - Tumor lysis syndrome ... #Differential #Diagnosis ... High #Magnesium #Table ... #Causes #Management
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Labs/Diagnosis: ... . systemic lupus ... erythematosus ( ... classification #rheumatology
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
Pancreatitis management ... abdominal compartment syndrome ... pain-dose ketamine infusion ... limit them as able ... Pancreatitis #Checklist #Diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... SLE-SSc-AlM overlap syndromes ... #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
(GBS), systemic ... lupus erythematosus ... (LEMS), systemic ... (SAMS-CI) • EMG ... #management #treatment