32 results
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Under 80 = microcytic ... in peripheral blood ... High in acute blood ... of substrate (e.g ... #Workup #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Framework by MCV Microcytic ... aciduria, Drugs (e.g ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
MCV - <80fL - "Microcytic ... disease, Acute blood ... MCV - >96fL - "Macrocytic ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... Normal Blood Smear ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Morphology Atlas • Microcytic ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... #differential #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Iron Deficiency (Eg ... Causes: Chronic Blood ... Other • e.g ... #Microcytic #Anemia ... #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology Microcytic ... Chemotherapy (e.g ... disease, McLeod blood ... differential #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Causes #Hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Megaloblastic Anemia ... (e.g. ... #Peripheral #Blood ... Smear #Analysis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
the peripheral blood ... infiltration (e.g ... Marrow suppression (e.g ... Intrinsic RBC defects (e.g ... Production #Index #hematology