28 results
Characteristic features of the rash are:

-Rough texture (like sandpaper)
-Worse in the skin folds e.g. groin, axilla,
features of the rash ... the skin folds e.g ... Pastia’s lines) #Clinical ... #Dermatology #Peds
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Petechial or purpuric rash ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... hemolytic anemia (e.g ... #Peripheral #Blood ... Smear #Analysis #hematology ... interpretation #clinical
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... Glomerulonephritis Myositis(5%) Blood ... symptoms #diagnosis #rheumatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Grooves • Any systemic ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... , breast CA - Hematologic ... neutrophils in the blood ... #diagnosis #dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Transfusions: Cellular blood ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... Irradiation #RBC #Blood ... #Indications #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... count, D-dimer, egg ... hemolytic #anemia #Hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... Maculopapular rash ... • Goodpasture syndrome ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology