17 results
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Iron deficiency anemia ... halt nail growth (e.g ... • Bacterial endocarditis ... • Nephrotic syndrome ... Systemic #Secondary #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
• Sickle Cell Anemia ... Septic Embolism (e.g ... Fat Embolism (e.g ... Mycotic Aneurysm (e.g ... Marfan's Syndrome
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
tuberculosis, Abscess, Endocarditis ... Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... (e.g. autoimmune
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Infectious • Endocarditis ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Increased Requirement (e.g ... • Pancreatic Disease ... Myelodysplastic Syndromes ... • Liver Disease ... Algorithm #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease ... #treatment #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Subacute bacterial endocarditis ... GI - Felty syndrome ... , Vasculitis (e.g ... fever - Bacterial endocarditis ... differential #diagnosis #rheumatology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Pre-existing valvular disease ... Congenital heart disease ... ↑ ESR, CRP • EKG ... Leukocytosis, anemia ... #diagnosis #management
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Anemia (common) ... Budd Chiari syndrome ... Recombinant cytokines (e.g ... kinase inhibitors (e.g