12 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... #Systemic #Lupus ... #rheumatology # ... management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... Special cases (e.g ... #rheumatology # ... pharmacology #levels #lupus ... #management
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... RA, SLE), Post-partum ... comparison #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... Erythematosus #SLE ... cerebritis #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... activation and/or medications
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... diseases: - 10% SLE ... tissue disorder (e.g ... . systemic lupus ... erythematosus (SLE
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Consensus Indications ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Hematology #BloodBank ... #Management
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... halt nail growth (e.g ... Discoloration • Medications ... • Nephrotic syndrome ... Systemic #Secondary #dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... erythematosus [SLE ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... GBS), systemic lupus ... erythematosus (SLE ... (SAMS-CI) • EMG ... myopathy #diagnosis #management