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diagnosis differential rheumatology causes management sle systemic activation acute algorithm bruising cerebritis classification cns cryoglobulinemia cryoglobulins disease fever fuo inflammatory
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... vein thrombosis Hematologic
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
• Reactive (e.g ... Enteropathic (e.g ... Erythematosus ... Sicca) Syndrome ... Enteropathic (e.g
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... #Erythematosus ... CNS #neurology #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... underlying disease (eg ... SJIA], systemic lupus ... erythematosus [ ... • Infection (eg
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Cardiac injury (e.g ... Pericardial perforation (e.g ... nodosa Rheumatoid arthritis ... Systemic lupus ... erythematosus
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 Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... tissue disorder (e.g ... . systemic lupus ... erythematosus ( ... SLE), rheumatoid arthritis
Differential Diagnosis of Acute Arthritis Crystal-induced arthritis: Calcium oxalate, gout, cholesterol, pseudogout, hydroxyapatite crystals Infectious arthritis: Bacteria, fungi,
Crystal-induced arthritis ... : Behçet syndrome ... sarcoid, systemic lupus ... erythematosus,* ... spondyloarthropathy (e.g
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 Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
SLE (systemic lupus ... erythematosus) ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus ( ... inflammatory disease (e.g ... Chemistry profile (e.g
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