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diagnosis differential management causes disease erythematosus sle systemic activation anemia autoimmune behcets bleeding cerebritis classification cns conditions criteria cryoglobulinemia cryoglobulins
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... disease, Vasculitis (e.g ... , Marfan syndrome ... differential #diagnosis #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Infected thrombosis, (e.g ... Lemierre's syndrome ... Malignancy: - Hematologic ... Inflammatory Diseases (e.g ... . autoimmune): Lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Erythematosus #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Diagnosis of Lupus ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
skin lesions (e.g ... Ocular disease (e.g ... vasculitis) • Arthritis ... Vascular lesions (e.g ... Diagnosis #criteria #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... tissue disorder (e.g ... . systemic lupus ... SLE), rheumatoid arthritis ... classification #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... inflammatory disease (e.g ... Chemistry profile (e.g ... diagnosis #testing #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... nonerosive inflammatory arthritis ... antiinflammatory properties e.g ... #Rheumatology #
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