8 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... #Management #Hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... Phaeochromocytoma Neurologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
unit activity on EMG ... of diazepam • EMG ... antibody that works ... TPO, TTG, etc EMG ... #neurology
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
endothelial cell activation ... other pathology (e.g ... (short-acting, e.g ... vasodilators (ERAs ... #nephrology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Diagnostic Workup ... non-organized (e.g ... or no deposits (e.g ... Complement pathway activation ... microangiopathy Treatment
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... sympathetic + ADH activation ... Treatment Overview ... liver insult (e.g ... #Hepatology #Nephrology