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diagnosis differential hematology algorithm management anemia erythematosus lupus nephrology secondary sle systemic acidosis autoimmune cerebritis chronic cns conjugated crisis cryoglobulinemia
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... bilirubin production (eg ... uptake and storage (eg ... miscellaneous causes ... (eg, spirochetal
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Dysplasias • (e.g ... Disease • GI (e.g ... • CNS Tumors (e.g ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... May be 10 (eg direct ... #Classification
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Hemoglobinopathies (e.g ... Membrane defects (e.g
Shock - Differential Diagnosis by Classification Reflex Syncope - Vasovagal syncope • Prolonged standing
Differential Diagnosis by Classification ... Medication side effect (e.g ... Subclavian steal syndrome ... Medication side effect (e.g ... #Table #Causes
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Genetic disorders (e.g ... Other humoral syndromes ... Hypercalcemia #Causes ... Differential #Diagnosis #Endocrinology
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 Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease (e.g ... #Anemia #MCV #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Hyperglycemia - Differential Diagnosis Algorithm Diabetes Mellitus: • Impaired Glucose Tolerance • Type I Diabetes • Type
• Cushing's Syndrome ... Hyperglycemia (e.g ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
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