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diagnosis differential rheumatology algorithm lupus management neurology peds sle vasculitis acidosis activation autoimmune bleeding bruising cerebritis cns cryoglobulinemia cryoglobulins dermatology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Thrombus (e.g ... Myeloproliferative disorders (eg ... Inflammatory • Systemic ... Lupus Erythematosus ... #Hematology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... RBC casts in urine ... May be 10 (eg direct ... damage from systemic ... #Classification
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Lupus Erythematosus ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
• Reactive (e.g ... Enteropathic (e.g ... Lupus Erythematosus ... Sicca) Syndrome ... Enteropathic (e.g
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g
Shock - Differential Diagnosis by Classification Reflex Syncope - Vasovagal syncope • Prolonged standing
Medication side effect (e.g ... • Multiple system ... Subclavian steal syndrome ... Medication side effect (e.g ... #Table #Causes
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... autoimmune disorders (Systemic ... lupus erythematosus
Causes of Acute Pericarditis: Infectious; Viral: Adenovirus Coxsackie virus A and B Echovirus Epstein-Barr virus Hepatitis Human immunodeficiency
Causes of Acute ... Cardiac injury (e.g ... Pericardial perforation (e.g ... Systemic lupus ... erythematosus
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 Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... underlying disease (eg ... lupus erythematosus ... • Infection (eg ... Diagnosis #Management #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... tissue disorder (e.g ... erythematosus ( ... diagnosis #types #classification
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