9 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Proteinuria often ... May be 10 (eg direct ... damage from systemic ... #Classification ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... (MPA) • SLE ... Protein deposition (eg ... #Nephrology #Differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... Lumbar Puncture, EEG ... #CNS #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... facial numbness), Encephalopathy ... AQP4-lgG disease; e.g ... autoimmune disorders (Systemic ... Manifestations #diagnosis #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... pupil (AACG) • Systemic ... symptoms and signs (e.g ... • Hypertensive encephalopathy ... CNS infection (e.g
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... • Malignancy (e.g ... Endocrine disorders (e.g ... (non-nephrotic proteinuria
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... tissue disorder (e.g ... . systemic lupus ... erythematosus (SLE ... diagnosis #types #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
by excretion (e.g ... its metabolism (e.g ... of Circulatory System ... - Compartment syndrome ... #typea #typeb #classification
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... , no hematuria/proteinuria ... Classification: ... liver insult (e.g ... #Hepatology #Nephrology