12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... #SLE #CNS #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... underlying disease (eg ... [SLE], AOSD) • ... Infection (eg, ... #Syndrome #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
May be 10 (eg direct ... damage from systemic ... #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
- Differential Diagnosis ... inhibitors, hepatorenal syndrome ... Secondary GNs: Due to systemic ... Post-infectious GN, Lupus ... #nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... • Malignancy (e.g ... Endocrine disorders (e.g ... #Systemic #Lupus
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... AQP4-lgG disease; e.g ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Labs/Diagnosis: ... tissue disorder (e.g ... . systemic lupus ... #types #classification
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
(systemic lupus ... infiltration (e.g ... Rare disorders, e.g ... - Vasculitis, e.g ... peds #pediatrics #diagnosis
Focal Hand Neuromyotonia 

Focal neuromyotonia in SLE.  A 42 year old with a 10 year
year history of Systemic ... lupus erythematosus ... EMG showed Neuromyotonia ... was diagnosed. ... clinical #video #neurology
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
(GBS), systemic ... lupus erythematosus ... (SLE), polymyositis ... (LEMS), systemic ... (SAMS-CI) • EMG