19 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Osmotic diuretics (e.g ... Loop diuretic (e.g ... Thiazides-type diuretics (e.g ... Potassium-sparing diuretics (e.g ... nephron #diuretics #pharmacology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Diuretic Sites of Action ... ) Loop agents (eg ... Diuretics #Sites #Action ... #nephrology #pharmacology
Oral anti-hypertensives with relative fast onset of action (Hypertensive Emergency)

The key concern with oral antihypertensive agents
fast onset of action ... up-titrating medications (e.g ... Emergency #Management #Pharmacology ... #Table #BloodPressure
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... differential #diagnosis #table ... #neurology
Muscarinic Receptor Agonists and Antagonists 
Muscarinic Receptor Agonists
Methacholine
 • Diagnosis of bronchial airway
Carbachol
 • Glaucorna (topical
due to Sjögren syndrome ... symptomatic bradycardia (e.g ... Scopolamine • Motion ... #Medications #Pharmacology ... #Table
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... transfusion • Allergic reaction ... (e.g. haloperidol ... Phaeochromocytoma Neurologic
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
concomitantly with caution ... - e.g. at lower ... #pharmacology #comparison ... dosing #drugs #table
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Mechanisms of Action ... Ozempic), or daily tablet ... side effects (e.g ... Receptor #Agonists #Pharmacology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... albuminuria) - Active ... Protein deposition (eg ... #Proteinuria #Nephrology