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differential management arthritis erythematosus lupus classification disease msk syndrome systemic vasculitis workup apml approach autoimmune bone clues conditions contusion ctchest
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... dz difficult to see ... #differential #diagnosis ... #causes #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... • Interstitial lung ... • Pulmonary ... • Shrinking lung ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... Like in this case ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... effusion, Restrictive lung ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... weeks) Can Be Caused ... arthritis • SLE ... #Diagnosis #MSK ... #rheumatology #
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... and fingers, or pain ... #sle #clues #system ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Arthritis: • Joint ... pain • Swan neck ... arthropathy • 90% joints ... #Rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
effusions, weight gain ... common • Imaging: CXR ... - pulmonary opacities ... #management #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... , fever, joint pain ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... titer, ACE level, CXR ... , and low back pain ... (to support a diagnosis ... #testing #Rheumatology
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