24 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Differential Diagnosis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... Deconditioning - Pain ... #causes #pulmonary
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... • Interstitial lung ... • Shrinking lung ... #pain #differential ... #diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
disease-associated interstitial lung ... PSS: Sjogren syndrome ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... Diagnosis: ... • A clinical diagnosis ... Rule out other causes ... #Rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... Demyelinating syndromes ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... effusions, weight gain ... common • Imaging: CXR ... - pulmonary opacities ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... symptoms are not caused ... e.g. incidental CXR ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
weight • Chest pain ... • Mounier-Kuhn syndrome ... in the adjacent lung ... of the affected lung ... parenchyma Diagnosis