34 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... Generally affects long ... BrighamChiefs #Bone #Joint ... #differential #diagnosis ... #causes #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... phenomenon (20%) Joints ... Arthritis in small joints ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... - Differential Diagnosis ... Chronic Chest Symptoms ... #Algorithm #Causes ... #Hematology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... of active pulmonary ... bacilli to bone/joints ... tissue damage - CXR ... for concomitant pulmonary
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... • Interstitial lung ... • Shrinking lung ... #differential #diagnosis ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... , dyspnea, +/- CXR ... Syndrome #TLS #diagnosis ... #management #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... constitutional symptoms ... weeks) Can Be Caused ... #Differential #Diagnosis ... #MSK #rheumatology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
pleural effusion on CXR ... inflammation tends to cause ... disease/pulmonary ... pathophysiology #signs #symptoms ... #diagnosis #ExtraArticular