21 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... common • Imaging: CXR ... - pulmonary opacities ... >3 symptoms, or> ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... , dyspnea, +/- CXR ... #TLS #diagnosis ... #management #hematology
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Mounier-Kuhn syndrome ... in the adjacent lung ... of the affected lung ... mycobacteria Treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
granulomas within the lungs ... are not caused ... e.g. incidental CXR ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... or serologies + symptoms ... Goodpasture's cause ... sparing of the lung ... #management #treatment
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
- Differential Diagnosis ... Temporomandibular joint ... the following symptoms ... subdural hematoma, lung ... • Associated symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... fluid balance, and CXR ... with pulmonary ... #diagnosis #comparison
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
inflammation of the joints ... and pain of the joints ... Causes: - Idiopathic ... Treatment: - Systemic ... #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... disease Caused ... on radioactive lung ... resolution of symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... bone pain, fever, joint ... manifestations, hypoxia, CXR ... • Tumor lysis syndrome ... #Oncology #Diagnosis