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diagnosis management nephrology differential syndrome algorithm classification microscopy renal aki clinical hematuria infectiousdiseases proteinuria syndromes urology workup barre blood encephalopathy
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
microscopy • Red cell casts ... • White cell casts ... infection • Hyaline casts ... • Granular casts ... #casts
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... chronic kidney diseases ... #Urine #Microscopy
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... WBCs, or urine ... → Urine culture ... proteinuria, RBC casts ... if cause not identified
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Simplified Approach to Acute ... PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts ... LorinskyMD #AKI #Acute
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... #Glomerular #Diseases ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/RBC casts ... Minimal change disease ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
1ml blood/liter urine ... basement membrane disease ... hematuria: - RBC casts ... of glomerular disease ... #urology #nephrology
Urinalysis & Urine Sodium Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
proteinuria as a disease ... • Urinary casts ... Acute Kidney Injury ... Acute Tubular Necrosis ... #UNa #casts #glucosuria
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
and less common diseases ... diagnosis and treatment ... Inflammatory causes ... Cogan syndrome • Acute ... BEE #Syndromes #neurology
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