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hematology rheumatology syndrome treatment blood causes differential product reactions activation adultonset atopic atopy behcet classification coagulation common cryofibrinogenemia cvid dermatitis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Differential Diaqnoses ... MAS, Visceral, DIC ... • Ocular: uveitis ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Avg age of DX ... late adulthood • Diagnosis ... conditions Diagnosis ... and M panel Management ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... artery aneurysms Diagnosis ... syndrome (Clinical Dx ... ) Differential Diagnosis ... #management #signs
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
helmet cells DDX ... • Severe Liver Disease ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
and Management ... screening for disease ... with established disease ... levels (VIII, IX ... #hematology
Lyme Disease - Diagnosis and Management Summary Lyme Disease Epidemiology: - Spirochete - Reservoir: small mammals & birds - Transmitted
Lyme Disease - Diagnosis ... and Management ... Pericarditis • Ocular ... to confirm the dx ... #Diagnosis #Management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
pulmonary emboli, and ocular ... Cryofibrinogenemia Diagnosis ... skin necrosis • DIC ... Cryofibrinogenemia #diagnosis ... #rheumatology #hematology
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... , erythematous macular ... Tailored therapy once dx ... STSS #treatment #management ... #diagnosis
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
- Differential Diagnosis ... Adult-onset Still's disease ... Preeclampsia Dermatologic ... Trauma: • Ocular ... #PhysicalExam
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... kidney failure DDX ... of underlying disease ... Activation #Syndrome #Diagnosis ... #Management #Hematology
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