17 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... of Pregnancy (AFLP ... (Hemolysis, Elevated ... #AFLP #obstetrics ... #hematology #diagnosis
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... (Hemolysis, Elevated ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Wilsons, Pregnancy - AFLP ... , HELLP • Moderate ... kwburak #LFTs #Elevated ... #hepatology #LiverFunctionTests
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Mild jaundice, Elevated ... , no necrosis HELLP ... features: Hemolysis, Thrombocytopenia ... #differential #diagnosis ... #icp #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential Diagnosis ... • Pregnancy - AFLP ... , HELLP Moderate ... Others #LFTs #Hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated ... - Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... #Differential #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #Algorithm #workup ... #hematology #testing
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... • Pregnancy: HELLP ... specificity to elevated ... #differential #diagnosis ... #algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
fibrinogen • Elevated ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... activity is the diagnostic ... available for rapid diagnosis ... Normal or slightly elevated ... #Workup #Hematology