3547 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... K, Elevated phos ... , Elevated uric
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... resp distress, elevated
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Physiologic Causes ... Pathologic Causes ... overdrive • Elevated ... Differential #Diagnosis #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... normal or slightly elevated ... Normal early on but elevated
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... falsely normal/elevated ... anion gap until it closes ... Abdominal pain, nausea ... DiabeticKetoacidosis #DKA #pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
fibrinogen • Elevated ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... intracellular calcium causes ... levels can be elevated ... #Pharmacology #Pathophysiology
D-dimer
Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
Elevated plasma ... age, which can cause ... Ddimer #dimer #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... CSF: Modestly elevated ... An elevated white ... the underlying cause ... with AEDs until cause
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... collection with EDTA Pathophysiology ... intracranial pressure - Elevated ... Phosphatase: • Other causes