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differential hellp obstetrics pregnancy thrombocytopenia ttphus apml compared defects differentiation disease erythemas hemophagocytic hepatitis hepatology hlh icp inherited leukostasis liver
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
) Three syndromes ... HELLP (Hemolysis, Elevated ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... HELLP (Hemolysis, Elevated ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... necrosis HELLP Syndrome ... (Hemolysis, Elevated ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... , Elevated uric ... #TLS #diagnosis ... #management #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
resp distress, elevated ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... >500 ng/mL • Elevated ... soluble CD25 • Elevated ... #management #treatment ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... if WBC > 5 or elevated ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Grey Platelet Syndrome ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
Erythema elevatum ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
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