35 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Time (PT) - Often Elevated ... (PTT) - Often elevated ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Hemolysis #Hemolytic #Anemia ... Causes #Workup #Hematology ... #Diagnosis * ... GrepMed Recommended Text
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Bayesian combination of 4T score with Heparin PF4 antibody titer to obtain the post-test probability of
obtain the post-test ... PF4Antibody #Bayesian #Diagnosis ... #Hematology #HITT ... Thrombocytopenia #Laboratory
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... Abnormal #APTT #Laboratory ... #Hematology #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
with elevated Mean ... - Differential Diagnosis ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... value is low, tests ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Defects: Sickle cell anemia ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... NEUROLOGIC - HEMOLYTIC ANEMIA ... ANA level above laboratory ... Direct Coombs’ test ... #Diagnosis #Rheumatology