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diagnosis dermatology clinical differential skinrash sle erythematosus management table algorithm causes classification cutaneous dermatomyositis manifestations myopathy myositis physicalexam secondary signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Photosensitivity, Butterfly rash ... Cranial nerve lesions ... , Aortic valve lesions ... symptoms #diagnosis #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
active and chronic lesions ... (C) : chronic lesions ... IV (A) : active lesions ... (C) : chronic lesions ... treatment #management #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... Discoid skin lesions ... • Discoid lupus ... differential #diagnosis #rheumatology
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
Mandibularis - The lesions ... #Clinical #Photo ... #Mandibularis #Rash
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... reddish-purple lesions ... Hypotension • Mucosal lesions ... : • Palpable Rash ... Autoimmune Vasculitis (lupus
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... scaly annular lesions ... plugging -> Discoid Rash ... Malar (butterfly) Rash
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
vasculitis Skin lesions ... • Painful skin lesions ... Papulo-necrotic lesions ... reticularis • Necrotic lesions ... gangrene Skin lesions
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
muscle weakness, rash ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... differential #diagnosis #comparison ... #rheumatology
Extrapulmonary manifestations of sarcoidosis. a. Endobronchial cobblestones (a nodular appearance of the tracheal wall mucosa). b. Diffuse
causing cystic lesions ... Lupus pernio (a ... chronic hardened red lesion ... neurosarcoidosis lesion ... manifestations #clinical #photo
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... #sle #comparison ... #table #rheumatology
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