46 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Cranial nerve lesions ... , Aortic valve lesions ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
active and chronic lesions ... (C) : chronic lesions ... IV (A) : active lesions ... (C) : chronic lesions ... treatment #management #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Discoid skin lesions ... • Discoid lupus ... differential #diagnosis #rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... scaly annular lesions ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... diagnosis #signs #symptoms
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
Mandibularis - The lesions ... #Clinical #Photo ... #Mandibularis #Rash
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial Rash ... reddish-purple lesions ... Hypotension • Mucosal lesions ... : • Palpable Rash ... Autoimmune Vasculitis (lupus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Typical Signs/Symptoms ... , Fever, Malar rash ... , Oral ulcers, Rash ... Erythematosus #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... Diagnosis and Lupus ... autoantibodies #signs #symptoms ... #differential #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
• Urogenital Lesions ... ) • Cutaneous Lesions ... 75%): acneiform lesions ... meningitis), MCC CNS symptoms ... #rheumatology #