31 results
diagnosis rheumatology oncology treatment cutaneous skin gammopathy hodgkins lymphoma manifestations vasculitis acquired activation adultonset aflp agglutinin anemia behcet capillary chronic
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Manifestations of Monoclonal ... Systemic amyloidosis, Nodular ... Cold agglutinin disease ... manifestations #dermatology ... #skin #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... capillary leak syndrome ... Ig deposition disease ... #Diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... ) Differential Diagnosis ... : monoclonal TNF-aIpha ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Hypergammaglobulinemic macular ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
- Idiopathic monoclonal ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Involving the Skin - Differential ... IgM deposits • Nodular ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... Vasculitis #skin #dermatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... • Clinical features ... involvement Differential ... #NonHodgkins #comparison ... #hematology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... appearing during the disease ... #differential # ... diagnosis #dermatology ... #oncology #clinical
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... • Ocular: uveitis ... #diagnosis #management ... #treatment #rheumatology
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