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oncology algorithm classification joint msk pain thrombocytosis approach cll disorders hodgkins lupus lymphocytic lymphoma sle vasculitis anemia aplastic arteritis autoimmune
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
deficiency) • Infection ... Sepsis • Non-infectious ... Myeloid Leukemia ... #Diagnosis #causes ... #Platelets #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Rheumatoid Arthritis ... Pseudotumor - Infectious ... History of Bleeding, Infection ... Age > 50 • Chronic ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Diagnosis Algorithm ... Myelogenous Leukemia ... Myelofibrosis Infectious ... #Causes #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Diagnosis Algorithm ... Infection • ... Myeloproliferative Disorder • Chronic ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... Infectious • ... Hepatic, Portal, ... • Lymphoma • Leukemia ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Thrombocytosis): • Acute infection ... myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Disorders: • Chronic ... Diabetes/DKA Infections ... : • helminth infections ... #Diagnosis #causes ... #hematology #basophils
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... drug reaction, infection ... Strongyloides infection ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Antineoplastic Viral Infection ... Idiopathic - Chronic ... • Rheumatoid Arthritis ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... #Hematology #Oncology
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