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management algorithm causes hodgkins leukemia lymphoma mds myelodysplastic ana anemia antibodies antinuclear cancer chronic classification cll differentiation erythematosus lad lupus
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Rheumatoid Arthritis ... Pseudotumor - Infectious ... History of Bleeding, Infection ... #Causes #Hematology ... #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... risk-stratification • Risks: infection ... #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
: >3 symptoms, or ... Diagnosis: Infection ... #APML #diagnosis ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Etiology: - Infections ... Diagnosis of B-Symptoms ... #oncology #diagnosis ... hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... bruising, bleeding, infection ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
: - Infection - ... Infant/child: - Infection-common ... ambulatory patients - Infections-common ... white blood cell aplasia ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Pure red cell aplasia ... #workup #oncology ... #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... • Nucleolar: Diffuse ... Lymphoproliferative Disorders, Infection ... ANA #patterns #rheumatology ... #diagnosis #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... petechiae) • Frequent infections ... • Parvovirus infection ... #diagnosis #hematology ... #oncology
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