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management chronic lymphocytic myelodysplastic algorithm anemia bariatric bypass cancer causes complications dermatology differentiation erythematosus gastric gastroenterology hemeonc lupus myelodysplasia neutropenia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... Myelodysplastic #Syndrome ... #MDS #Diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... aplasia • ITP ... • Richter’s Syndrome ... syndrome • Smoldering ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Neutropenia - recurrent infections ... Constitutional Syndromes ... Idiopathic • Infections ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Cell Leukemia ... • Parvovirus infection ... #diagnosis #hematology ... #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
: - Infection - ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... Infant/child: - Infection-common ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: Infection ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
in adults • Disorder ... Complications: 1) Infection ... Lauren Banaszak, MD ... uw_IMresidency #CLL ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... dermatosis (Sweets Syndrome ... Upper respiratory infection ... gastrointestinal infection ... #diagnosis #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren syndrome ... fibromyalgia) • Infections ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome
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