3004 results
Endotypes and mechanisms involved in anaphylaxis. 

#anaphylaxis #Endotypes #pathophysiology
Endotypes and mechanisms ... #anaphylaxis #Endotypes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... C-ANCA): GPA >>> MPA ... > eGPA • MPO-ANCA ... P-ANCA): eGPA, MPA
Monkeypox - Virology

Causative Agent: Monkeypox virus (MPV)
Year of Discovery: 1958
Genome: Double-stranded DNA
Variants and Genotypes: 2 clades
Primary
Monkeypox virus (MPV ... Variants and Genotypes ... #MPX #MPV #monkeypox
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (MPA ... associated with MPO ... polyangiitis - MPO ... polyangiitis - MPO ... #CANCA #PANCA #MPO
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... polyangiitis - MPO ... PR3 (80-90%) > MPO ... Churg-Strauss) - MPO
Drugs Causing Acute Pancreatitis

Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA ... Induction: GC+MTX ... #Polyangiitis #MPA
Causes of Erythema Nodosum - Mnemonic

NO cause found in 60% of cases
Drugs (antibiotics e.g., sulfonamides, amoxicillin)
Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Nodosum #Mnemonic #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/RBC casts ... polyangiitis (MPA ... Diagnosis #Algorithm #Causes
Causes of Prolonged Emergence - Anesthesiology

Prolonged Drug Action:
• Overdose 
• Hypothermia (< 33 C) 
• Incr
Causes of Prolonged ... Metabolic Causes ... Mark Harris, MD MPH ... Anesthesiology #Causes