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Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Hemoglobin - Enzyme ... Diagnosis #Causes #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
(Vacuoles, E1 enzyme ... vasculitis • Hematologic ... criteria for 1) hematologic ... UBA1 = major E1 enzyme ... Autoinflammatory #Somatic #rheumatology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Membrane defects, Enzyme ... Diagnosis #Algorithm #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
P-glycoprotein enzymes ... Inducers of these enzymes ... Chemotherapy #Oncology #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
, Spiders - Enzyme ... Differential #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
elliptocytosis - RBC Enzyme ... Algorithm #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Intrinsic Causes: • Enzyme ... classification #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
elevated liver enzymes ... elevated liver enzymes ... including liver and hematologic ... diagnosis #management #hepatology
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis - Chloroquine (Aralen)*
Urate-Oxidase Enzyme ... Urate-Oxidase Enzyme ... #Pharmacology #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
deficiency, Other enzyme ... Algorithm #workup #hematology
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