842 results
diagnosis symptoms signs differential management pharmacology cardiology endocrinology nephrology syndrome algorithm causes hematology hepatology infectiousdiseases complications msk lifecycle ophthalmology cdc
Steroid Synthesis Pathway (OH, hydroxy; HSD, hydroxysteroid dehydrogenase; DHEA, dehydroepiandrosterone; pink, common enzymes affecting CAH, purple –
; pink, common enzymes ... Pathway #metabolism #pathophysiology
Heme Synthesis Pathway Enzymes 1. ALA Synthase 2. ALA Dehydratase 3. Porphobilinogen deaminase 4. UP Ill Synthase 5. UP Ill Decarboxylase 6. Coproporphyrinogen
Synthesis Pathway Enzymes ... Synthesis #Pathway #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Elevated Liver Enzymes ... Complications #pathophysiology
Complications of Measles: Pathogenesis and Clinical Findings • ADEM -> Fever, headache, neck stiffness, BBD, mental
elevated liver enzymes ... signs #symptoms #pathophysiology
Purple Urine Bag Syndrome Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine Tryptophan → Indoxyl
sulfate → Sulfatase enzyme ... Syndrome #PUBS #pathophysiology
Uric Acid Homeostasis In the liver, purines are metabolized to uric acid. The last step in purine
metabolism involves an enzyme ... In animals, the enzyme ... Homeostasis #Gout #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme ... differential #diagnosis #pathophysiology
Osteoarthritis (OA): Clinical findings • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
of proteolytic enzymes ... Osteoarthritis #OA #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
puncture holes), enzyme-mediated ... #Inflammation #pathophysiology
Pathophysiology of ACE inhibitor-induced angioedema: Angioedema is a vascular reaction associated with tissue (subcutaneous, submucosal) edema
Pathophysiology ... inhibition, these enzymes
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