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differential classification erythematosus hematology lupus management signs sle symptoms acute causes nephrology syndrome workup aki ana antibodies antibody antineutrophil antinuclear
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... StanfordChiefs #ANCA ... #diagnosis #algorithm ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... Vasculitis: • ... + 60% • Eosinophilic ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (MPA), and eosinophilic ... polyangiitis - MPO>PR3 Eosinophilic ... PR3 Anti-GBM disease ... MPO #PR3 #Diagnosis ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • EGPA: - Eosinophilia ... Differential Diagnosis ... purpura: strong sign ... #rheumatology #
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... vasculitis (Eosinophilic ... Immune Complex: Systemic ... Rheumatoid arthritis, Systemic ... #differential #diagnosis
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
central nervous system ... small vessels - ANCA-associated ... - systemic ... #Rheumatology # ... Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... progressive) EGPA (Eosinophilic ... Polyangiitis): • Eosinophilia ... #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Nodosa (PAN), ANCA ... associated vasculitis ... Arthritis (RA), Systemic ... #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Cough - Diagnostic Schema Infectious: URTI, LRTI, Bacterial, Viral Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body Airway Disease:
Cough - Diagnostic ... Bronchiectasis Other organ/systemic ... CHF, Autoimmune Vasculitis ... mycobacterial), Eosinophilic ... #Differential #Algorithm
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