32 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
can present with rash ... including heliotrope rash ... , Shaw sign, holster ... sign, and Gottron's ... #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology ... #eosinophilia
An Approach to the Unknown Rash: Erythematous Rash 

#Diagnosis #Dermatology #Erythematous #Rash #Differential #Algorithm #Nikolsky #Sign
to the Unknown Rash ... #Diagnosis # ... Dermatology #Erythematous ... #Rash #Differential ... Algorithm #Nikolsky #Sign
Bullous pemphigoid and pemphigus vulgaris

Comparison Table via Physical Examination, Nikolsky Sign and Differential Diagnoses

#Diagnosis #Dermatology #Bullous
Examination, Nikolsky Sign ... and Differential ... Diagnoses #Diagnosis ... #Dermatology #Bullous ... #Comparison #Table
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
involve DIP • Myositis ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... Arthralgia / arthritis, Myositis ... Erythematosus #SLE #Signs ... #Symptoms #diagnosis ... #rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... Inclusion Body Myositis ... Inflammatory #Myopathies #differential ... #rheumatology # ... table
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... anemia 4% - Myositis ... (aPL) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... muscle weakness, rash ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology