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diagnosis management cancer leukemia mds myelodysplastic aki apml chronic classification dermatology differential differentiation encephalopathy hemophagocytic hlh injury kidney lymphocytic lymphohistiocytosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... transformation to acute ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... Classification #Nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelogenous Leukemia (CML ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... general feeling of ill ... , breast CA - Hematologic ... Treatment: - Systemic ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms: Acute ... Anterior circulation: MCA ... , ADEM, Acute toxic ... epilepticus Treatment ... underlying cause • Treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... Low or absent NK cell ... Ferritin >500 ng/mL ... #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... algorithm 2018. ... clonal evolution to acute ... #algorithm #hematology
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